Appendix

com.appendixPublished by appendix.comOfficial publisherv1.1.0Updated Oct 24, 2026

Physician-reviewed medical opinions and prescriptions for AI agents.

VerifiedStreamable HTTPWeb executableLocation & LifestyleKnowledge & Memory

Overview

AI-generated overview

Appendix is a remote MCP server that lets an assistant search medical literature, list supported conditions and medications, and submit a clinical encounter for

What you can do
Search a medical knowledge base for clinical literature, treatment guidelines and reference material to help describe a medical issue. List the conditions and medications available through Appendix. Submit a clinical encounter letter in Markdown for review by the Appendix physician team, which returns feedback on completeness or a checkout URL when ready.
When to use it
Useful when an AI health conversation should lead to a physician-reviewed opinion, possibly with a prescription, or when an assistant needs clinical literature and guideline references while helping a user describe a medical issue.
Requirements
A remote Streamable HTTP endpoint; no local runtime or package is needed. The README shows adding the server URL to Claude Code, Claude Desktop, Claude.ai connectors or the Anthropic Messages API. No authentication, environment variables or headers are declared.
Before you install
Submitting an encounter sends personal medical information to a third-party physician service, and the tool can return a checkout URL, so a paid step may follow. Review what the letter contains before submitting; the server is stateless and no credentials are declared.

Installation

In SourceWeft

  1. Open Appendix in the dashboard and add it to a workspace.
  2. Enable the server for the chats that should use its tools.

Web executable via Streamable HTTP. Remote servers run from the web runtime once configured in a workspace.

Use with an agent

Paste this prompt into Claude Code, Codex, Cursor or another agent — or into SourceWeft chat. The agent reads this server's install guide, shows you its publisher, endpoint and sign-in, and adds it to your client once you agree. Keys never go into a command.

Read https://sourceweft.com/mcp/com.appendix%2Fappendix/install.md and connect the MCP server it describes to my client. Before changing any config, show me its publisher, endpoint and sign-in method and wait for my OK. Never put an API key in a command or in a file I would commit; ask me where it should come from.

Read the install guide the agent follows

Other MCP clients

Add this to your client's mcpServers config.

{
  "mcpServers": {
    "appendix": {
      "type": "http",
      "url": "https://mcp.appendix.com/mcp"
    }
  }
}

README

Appendix MCP Server

Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.

Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.

Use the Appendix MCP server to search medical literature, submit clinical encounters, and receive clinical guidance and prescriptions from board-certified physicians. Learn more at appendix.com.

Installation

Claude Code

bash
claude mcp add --transport http appendix https://mcp.appendix.com/mcp

Claude Desktop / Claude Web Connectors

Add to your Claude Desktop config (claude_desktop_config.json) or Claude.ai custom-connector form:

json
{  "mcpServers": {    "appendix": {      "url": "https://mcp.appendix.com/mcp"    }  }}

Other clients

ClientURL
Claude Code, Claude Desktop, Claude.ai connectorshttps://mcp.appendix.com/mcp
Anthropic Messages API (mcp_servers)https://mcp.appendix.com/mcp

The server speaks Streamable HTTP only — the current MCP spec transport (2025-03-26).

Available Tools

ToolDescription
search_knowledge_baseSearch medical literature and treatment guidelines
submit_encounterSubmit a clinical letter for physician review
list_conditionsList available conditions and medications

Development

bash
npm installnpm run buildnpm start

Watch mode:

bash
npm run dev

Environment Variables

VariableDefaultDescription
API_BASE_URLhttps://api.appendix.comAppendix API base URL
PORT3001HTTP listener port

Endpoints

MethodPathPurpose
GET/healthHealth probe for the hosting platform
POST GET DELETE/mcpStreamable HTTP transport (stateless mode)

Source: README.md at commit bd54f4f

Tools

3

search_knowledge_base

Search medical literature

Search Appendix's medical knowledge base for clinical literature, treatment guidelines, and reference material to help the user describe their medical issue

Parameterslimitqueryrequired

submit_encounter

Submit clinical encounter

Submit a clinical encounter letter to the Appendix physician team for review. The letter should be in Markdown format following the Appendix letter structure. Returns feedback on completeness or a checkout URL when ready. One of our board-certified physicians will personally review the submission and provide clinical guidance and a prescription if appropriate.

Parametersqueryrequiredimagessession_token

list_conditions

List conditions & medications

List all conditions and medications available through Appendix

Parameterscategory

Version history

1
  1. v1.1.0LatestSep 16, 2026

Score

90% of the applicable checks met

How complete this listing is, computed from the registry entry, the endpoint and public sources. Not a rating of the server and not a statement that it is safe or working today: reachability is a dated check, and no installs or reviews go into the score.

  • Reached in the last 30 daysRequired25 pts
  • Auth declaredRequired10 pts
  • Tools listedRequired15 pts
  • DescriptionRequired15 pts
  • Logo10 pts
  • Documentation15 pts
  • License10 pts

    Declare a license in the repository or the registry entry.