New Era Syringe Pump

io.github.K-Dense-AIPublished by GitHub account K-Dense-AIv0.1.2Updated Nov 10, 2026

MCP server for New Era Pump Systems syringe pumps (NE-1000 family, RS-232).

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Overview

AI-generated overview

MCP server that lets an AI assistant control New Era NE-1000-series syringe pumps over RS-232: set the syringe, infuse or withdraw a volume, and stop.

What you can do
  • Set up the syringe from manual presets or a measured inside diameter, and list available presets with their rate ranges
  • Start infusions or withdrawals at a chosen rate and volume, and stop the pump immediately
  • Read pump status, alarms, direction, rate, target volume and accumulated dispensed volumes
  • Reset the dispensed-volume accumulators and reconnect after a power cycle or cable change
  • Inspect connection details and the raw command log for debugging and record-keeping
When to use it
Useful when you have a New Era NE-1000-family pump on a serial or serial-to-Ethernet link and want an assistant to run precise infuse/withdraw steps, check status, or stop the pump. It is a good fit for scripted lab protocols and for trying the workflow without hardware via the built-in simulator.
Requirements
Runs locally as a Python package (uvx labmcp-new-era) over stdio; desktop only. Needs the pump in Address and Basic mode, a serial or TCP address via LABMCP_ADDRESS (for example serial:///dev/ttyUSB0 or tcp://host:port), and a free serial port per server. Optional LABMCP_READ_ONLY, LABMCP_LIMITS and LABMCP_SIMULATE.
Before you install
Infuse and withdraw physically move liquid and return as soon as pumping starts, so long runs continue after the call; they also overwrite phases 1-2 of the pump's stored program. Changing the syringe diameter resets volume counters. Safe mode (CRC framing, watchdog) is not supported. The server is tested only against a simulator, not real hardware, so verify on your instrument first; use read-only mode and tight limits where risk matters.

Installation

In SourceWeft

  1. Open New Era Syringe Pump in the dashboard and add it to a workspace.
  2. Enable the server for the chats that should use its tools.

Desktop only via STDIO. STDIO servers start a local process, so they need the SourceWeft desktop host.

Other MCP clients

Follow the launch instructions in the repository.

README

New Era Syringe Pump — MCP Server

Let an AI agent set up the syringe, infuse or withdraw an exact volume at a set rate, follow the dispensed volume and stop New Era Pump Systems syringe pumps through their documented RS-232 Basic-mode command set.

Packagelabmcp-new-era
InstrumentsNE-1000 Multi-Phaser, NE-1002X, NE-1010, NE-4000 two-channel, NE-500 OEM, NE-8000 high-pressure, and other NE-1000-series pumps with an RS-232 port
InterfacesRS-232 (RJ-11 "To Computer" jack), USB via New Era's CBL-USB232 or any USB-RS-232 adapter, serial-to-Ethernet adapters
ProtocolNew Era RS-232 Basic mode (NE-1000 User Manual, Publication #1200-01, section 10; same command set in the NE-4000 manual)
Status🧪 simulated: tested against a wire-level simulator, not yet verified on hardware. Report a hardware test

Try it without hardware

bash
uvx labmcp-new-era --simulate --check

The simulator pumps in real time. Add --option sim_speed=20 to make simulated time run 20× faster for demos.

Connect your pump

  1. Pump setup: the pump must be in Address mode (the default, Ad:nn in the Setup menu) and in Basic communications mode (the default; if someone enabled Safe mode, send SAF0 from a terminal or run a master reset). Factory settings are 19200 baud, 8N1, network address 0.
  2. Cable: New Era CBL-PC-PUMP-7 (plus CBL-USB232 for USB) into the pump's To Computer jack.
  3. Find the port: uvx labmcp ports
  4. Test the connection:
    bash
    uvx labmcp-new-era --address /dev/ttyUSB0 --check            # Linuxuvx labmcp-new-era --address /dev/tty.usbserial-XXXX --check  # macOSuvx labmcp-new-era --address COM5 --check                    # Windows
    Non-default baud rates go in the address: serial://COM5?baudrate=9600.
  5. Pump networks: up to 100 pumps can be daisy-chained (To Network → next pump's To Computer), each with its own address 0–99. Run one server per pump and select it with --option pump_address=3. Without the option, commands carry no address prefix, which the pumps treat as address 0.

Add to your MCP client

Claude Code

bash
claude mcp add syringe-pump -- uvx labmcp-new-era --address /dev/ttyUSB0

Claude Desktop / Cursor / Windsurf (claude_desktop_config.json, .cursor/mcp.json, …)

json
{  "mcpServers": {    "syringe-pump": {      "command": "uvx",      "args": ["labmcp-new-era", "--address", "/dev/ttyUSB0"]    }  }}

Each server controls one pump (--option pump_address=N on a daisy-chained network). A serial port can only be opened by one server at a time, so to drive two pumps at once give each its own cable/port. Add --read-only to allow monitoring but block pumping and settings changes.

Tools

ToolKindDescription
clear_dispensed_volume🎛 controlReset the infused and withdrawn volume accumulators to zero. Only possible while stopped.
get_command_log👁 readReturn the most recent raw commands sent to / replies received from the instrument (newest last). Useful for debugging and for recording what was done.
get_connection_info👁 readReport which instrument is connected (identity, address, simulated or real), whether the server is read-only, and the active safety limits. Call this first.
get_dispensed_volume👁 readReturn the accumulated infused and withdrawn volumes (pump command DIS).
get_status👁 readReport what the pump is doing (infusing/withdrawing/stopped/paused, alarms), the syringe diameter, rate, target volume, direction and the accumulated dispensed volumes.
infuse⚠️ hazardPush volume_ml out of the syringe at rate_ml_min, then stop. Returns as soon as pumping has started, with the estimated duration. Requires the correct syringe diameter (set_syringe) and a stopped pump. Overwrites phases 1-2 of the pump's stored Pumping Program.
list_syringe_presets👁 readList the syringe inside diameters from the New Era manual's reference table (BD, Monoject, Terumo, HSW Norm-Ject, Poulten & Graf glass, stainless steel, SGE, Hamilton), with the NE-1000 rate range each allows. Use a name with set_syringe.
reconnect🛑 safetyClose and re-open the connection to the instrument (e.g. after it was power cycled or a cable was re-plugged).
set_syringe🎛 controlSet the syringe inside diameter, either from a preset or a measured value. The pump must be stopped. Changing the diameter also resets the dispensed-volume accumulators and may switch the pump's volume units (µL below 14.0 mm, mL above).
stop_pump🛑 safetyStop the pump immediately (STP). A paused program is also cancelled so it cannot resume.
withdraw⚠️ hazardPull volume_ml into the syringe at rate_ml_min, then stop. Returns as soon as pumping has started. Make sure the syringe has room for the volume. Overwrites phases 1-2 of the pump's stored Pumping Program.

Safety limits

LimitDefaultMeaning
max_rate_ml_min10 mL/minHighest pumping rate infuse/withdraw may set
max_volume_ml20 mLLargest volume a single infuse/withdraw may move

Override at launch: --limit max_rate_ml_min=0.5 --limit max_volume_ml=2 (e.g. for a microfluidic chip). The pump itself also refuses rates outside what the syringe diameter allows (?OOR), and the server explains that range.

Example prompts

  • "Set the pump for a BD 10 mL syringe and infuse 2 mL at 0.5 mL/min into the reactor. Tell me when it's done."
  • "Withdraw 250 µL at 100 µL/min, then report how much was actually withdrawn."
  • "What's the pump doing right now? Is there an alarm?"
  • "Our syringe is a 5 mL glass Hamilton with 10.30 mm inside diameter — set that, then prime by infusing 0.1 mL at 1 mL/min."
  • "Stop the pump now."

Notes

  • Diameter is everything. The pump converts volume to plunger travel from the inside diameter. Presets come from the reference table in the NE-1000 manual (section 12.7); always confirm against your syringe manufacturer's data. Changing the diameter resets the dispensed-volume counters, and the pump works in µL for diameters ≤ 14.0 mm and in mL above.
  • Stored program is overwritten. infuse/withdraw program phase 1 as a RATE phase (rate, volume, direction) and phase 2 as STOP, so the pump stops after the volume. Any multi-phase Pumping Program you stored on the pump is overwritten in phases 1–2.
  • Rounding. The pump accepts at most 4 significant digits (and 3 decimals). The server picks the rate units (µL/min, mL/min, µL/h, mL/h) that represent your rate most precisely and reports the exact values it sent.
  • infuse/withdraw return as soon as pumping starts; long infusions keep running after the tool call. stop_pump sends STP and, if the program is then paused, a second STP so the program cannot be resumed by accident.
  • The first reply after the pump powers up is a reset alarm (A?R). The server acknowledges it and repeats the command; stall alarms (A?S) are reported, never retried.
  • Safe mode is not supported. Safe mode (CRC-16 framing, communication watchdog) is recommended by New Era for production. This server uses Basic mode only.
  • The NE-300 "Just Infusion" manual documents no RS-232 interface, so it is not supported. Syringe rate ranges quoted by list_syringe_presets are for the NE-1000; other models (e.g. NE-8000, NE-1010) have different speed ranges.

Hardware verification

ModelFirmwareInterfaceVerified byDate
none yet: be the first

Source: servers/biology/new-era-syringe-pump/README.md at commit 46545ea

Tools

0
SourceWeft has not started this package in its sandbox yet, so its tools are not known.

Version history

2
  1. v0.1.2LatestSep 27, 2026
  2. v0.1.0Sep 26, 2026

Score

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  • Reached in the last 30 days25 pts

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  • Auth declared10 pts

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  • Tools listed15 pts

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  • DescriptionRequired15 pts
  • Logo10 pts
  • Documentation15 pts
  • License10 pts