UniProt MCP

A local MCP server that gives an assistant read-only access to UniProtKB protein data: entries, sequences, features, GO annotations, taxonomy and ID mapping.

What you can do

Look up UniProtKB entries and retrieve protein sequences and sequence features such as domains and sites, read-only throughout. Query Gene Ontology annotations and taxonomy information linked to entries. Map identifiers between UniProt and other databases. All access is read-only, so the assistant can inspect and cross-reference protein records but cannot modify them.

When to use it

Useful when working with protein or proteomics questions and you want the assistant to pull authoritative UniProtKB records, sequences, functional annotations or identifier mappings instead of relying on memory.

Requirements

Runs as a local process over stdio, installed from the PyPI package uniprot-mcp, so a Python environment is needed. No authentication, environment variables or headers are declared. Network access to UniProt services is implied by the data it reads.