BioCosm

io.github.nhovertePublished by GitHub account nhovertev1.0.0Updated Oct 24, 2026

Biotech intelligence for AI agents: drugs, targets, diagnostics, PoS estimates, and writeups.

VerifiedStreamable HTTPWeb executableKnowledge & Memory

Overview

AI-generated overview

BioCosm gives an assistant biotech intelligence on drugs, targets, diagnostics, probability-of-success estimates, and writeups.

What you can do
BioCosm is a remote MCP server that supplies biotech intelligence to AI agents. According to its registry description, it covers drugs, targets, diagnostics, probability-of-success (PoS) estimates, and writeups. No tool list is published, so the exact operations and output formats are not documented here.
When to use it
Consider it when an assistant needs biotech domain context such as drug, target, or diagnostic information, or probability-of-success estimates and written analyses. It is less clearly useful if you need documented, granular tool control, since no tool list is provided.
Requirements
It runs as a remote streamable HTTP endpoint at biocosm-mcp.fly.dev, so no local runtime or package install is needed. The manifest declares no authentication, environment variables, or headers, and no account or API key is listed.
Before you install
The server is third-party and hosted remotely; queries and any data you include are sent to that endpoint. No authentication is declared, so do not send confidential or regulated information. No tool list is published, so review what it actually does before relying on its outputs.

Installation

In SourceWeft

  1. Open BioCosm in the dashboard and add it to a workspace.
  2. Enable the server for the chats that should use its tools.

Web executable via Streamable HTTP. Remote servers run from the web runtime once configured in a workspace.

Use with an agent

Paste this prompt into Claude Code, Codex, Cursor or another agent — or into SourceWeft chat. The agent reads this server's install guide, shows you its publisher, endpoint and sign-in, and adds it to your client once you agree. Keys never go into a command.

Read https://sourceweft.com/mcp/io.github.nhoverte%2Fbiocosm/install.md and connect the MCP server it describes to my client. Before changing any config, show me its publisher, endpoint and sign-in method and wait for my OK. Never put an API key in a command or in a file I would commit; ask me where it should come from.

Read the install guide the agent follows

Other MCP clients

Add this to your client's mcpServers config.

{
  "mcpServers": {
    "biocosm": {
      "type": "http",
      "url": "https://biocosm-mcp.fly.dev/mcp"
    }
  }
}

Tools

13

search_nodes

Search BioCosm nodes by name, gene symbol, target, therapeutic area, or company. Results are ranked: exact name/brand matches first, then partial name matches, with a node-type prior (canonical drug/diagnostic nodes rank above gene-target nodes, which rank above ChEMBL salt-form duplicates). Nodes matched only via description/company/area rank last. Each result includes a `name` field for disambiguation.

Parameterslimitqueryrequired

get_node

Get full details for a single BioCosm node: identity and all name aliases, classification, gene targets and mechanism, therapeutic areas, companies, revenue history where available (sparse: ~100 drugs, mostly blockbusters, as annualized quarterly estimates; source links when present), probability-of- success predictions for pipeline drugs (with confidence intervals and contributing factors), structured clinical trial outcomes, external cross-references, and writeup availability. Empty fields mean "not in BioCosm's coverage," NOT zero or absent in reality.

Parametersnode_idrequired

get_writeup

Get the full writeup for a BioCosm node, including all sections, citations, structured data, and validation score.

Parametersnode_idrequired

list_by_therapeutic_area

List all nodes in a given therapeutic area.

Parametersarearequiredlimit

get_company_portfolio

Get a company's full drug/diagnostic portfolio from BioCosm.

Parameterscompany_namerequired

get_stats

Get a high-level overview of the BioCosm database: total nodes, writeups, companies, breakdowns by type/status/domain, validation scores, and recent pipeline runs.

Takes no parameters.

get_staleness_report

Get writeup staleness report: overall stats, top stale nodes, data source freshness.

Parameterslimit

get_node_freshness

Get freshness details for a single node: writeup age, enrichment hash match, staleness score, validation score.

Parametersnode_idrequired

find_by_target

Find all drugs that target a specific gene/protein.

Parameterslimittarget_generequired

find_by_phase

List drugs/diagnostics at a specific clinical phase.

Parameterslimitphaserequirednode_type

get_pos_score

Get the Probability of Success estimate for a node, including the base rate, adjustment factors with reasoning, confidence interval, and model version. Returns None for nodes without a PoS score (typically only late-stage pipeline drugs are scored).

Parametersnode_idrequired

get_coverage

Report BioCosm's actual data coverage so you never mistake missing data for a real-world zero. An empty or absent field on a node means "not in BioCosm's data," never a true zero. BioCosm is AI-generated and may contain errors.

Takes no parameters.

Version history

1
  1. v1.0.0LatestSep 16, 2026

Score

83% of the applicable checks met

How complete this listing is, computed from the registry entry, the endpoint and public sources. Not a rating of the server and not a statement that it is safe or working today: reachability is a dated check, and no installs or reviews go into the score.

  • Reached in the last 30 daysRequired25 pts
  • Auth declaredRequired10 pts
  • Tools listedRequired15 pts
  • DescriptionRequired15 pts
  • Logo10 pts
  • Documentation15 pts

    Declare a GitHub repository with a README, or serve resource_documentation in the OAuth protected-resource metadata.

  • LicenseNot applicable

    A hosted service is used under its provider's terms, so no license is expected here. This check is left out of the percentage.