Ucsc Genome Mcp

io.github.mrfentmen由 GitHub 账号 mrfentmen 发布v1.0.1更新于 Nov 3, 2026

UCSC Genome Browser: list genomes, fetch DNA ranges and search genes by name

已验证STDIO仅桌面知识与记忆数据与分析

概览

AI 生成的概览

查询 UCSC Genome Browser:列出基因组与染色体、获取 DNA 序列区间,并按名称搜索基因。

可以做什么
  • 列出 UCSC 托管的基因组,可按名称、物种或描述筛选
  • 列出某个装配体的染色体与支架及其大小
  • 获取指定坐标区间的 DNA 序列,并给出长度、GC 含量与 N 数量
  • 按基因或特征名称搜索装配体,返回匹配位置及坐标
适用场景
适合需要助手在对话中查询参考基因组装配体、染色体大小、特定位点的原始序列,或某个基因的坐标时使用。
运行要求
以本地进程方式通过 stdio 运行,来自 npm 包 @mrfentmen/ucsc-genome-mcp;需要 Node.js 以及访问 UCSC 数据的网络连接。未声明需要 API 密钥或环境变量。
安装前请注意
仅对 UCSC 公开数据进行只读查询,未描述凭据、付费或写入操作。结果取决于 UCSC 服务可用性,且坐标需按该装配体自身的坐标系给出。

安装

在 SourceWeft 中

  1. 打开 控制台中的 Ucsc Genome Mcp,将其添加到工作区。
  2. 为需要使用其工具的对话启用该服务。

Desktop only,通过 STDIO。 STDIO 服务会启动本地进程,因此需要 SourceWeft 桌面宿主。

其他 MCP 客户端

参照 仓库 中的启动说明。

README

awesome-servers

One repo for three families of servers, each subtree keeping its own layout and tooling so it can still be built, run and published on its own.

SubtreeWhat it holdsRun one
mcp/338 TypeScript MCP servers, plus 1107 published packages in published/cd mcp/servers/<slug> && npm install && npm run build
acp/79 Python ACP agentspython3 acp/agents/<name>/agent.py
a2a/37 Python A2A servers plus the shared a2a_kitpython3 a2a/servers/<name>/server.py
watchd/a threshold watcher that runs the feeds between editor sessionspython3 watchd/watchd.py --config conditions.json --loop
site/the published site: registry with search, the public-feed atlas, watchd planshttps://mrfentmen.github.io/awesome-servers/

Most servers read public data with no key of their own; the ones wrapping a vendor API take that vendor's key. Nothing in this repo asks a caller to pay. On 2026-10-17 the licence machinery was removed for good: the per-tool src/license.ts gates are gone from the MCP servers, and the A2A and ACP trees no longer carry the hosted licence-gateway half — the skills that used it now answer with an explicit not-implemented stub. Nothing here asks a caller to pay, and nothing they run is refused with a buy link.

Nothing here is generated: each subtree's README says what its servers read, and every server has its own unit tests (mcp/servers/<slug>/tests, acp/agents/<name>/tests, a2a/servers/<name>/tests) plus a live smoke check (tools/smoke*.py, a2a/tools/smoke_all.py).

Novel and original

Nearly all of this is first-of-its-kind work, not a port of an existing catalogue. Before each server or agent was built, it was checked against the official tool lists (the MCP registries, agentclientprotocol.com's agent list and registry) and a live GitHub search for the same domain, and the research logs record what was found and why it still counted as missing — see mcp/MISSING.md, acp/MISSING.md and a2a/docs/. Highlights:

  • The MCP side holds TypeScript servers, one npm package each, and 1039 published packages under published/; mcp/MISSING.md documents the check that preceded every build: what was searched, what was skipped and why the domain still counted as uncovered.
  • On the ACP side there were zero domain agents before this repo — every agent on the official list was a coding agent. These 79 Python agents are the first non-coding ACP agents, and several use protocol surfaces no other agent uses in production (session/request_permission for dataset reads, fs/write_text_file for a briefing file, session/cancel for a conditional watch, image content blocks, a live SSE push feed), each proved-unused in the wild by search at build time. Two more firsts carry their own proof: the orchestrator is an agent whose feeds are agents — it spawns sibling repo agents as real ACP child processes and merges their answers — and the nyc pack is the first multi-agency city surface.
  • acp/MISSING.md doubles as the public-feed atlas: every keyless feed probed live, with its date, what it answered and whether it still works. The published site renders that table at https://mrfentmen.github.io/awesome-servers/atlas.html.
  • The pattern across all three subtrees is the same thesis: wrap one real, keyless public dataset, answer honestly about what the feed did and did not say, and keep the whole thing small, tested and self-contained.

Publishing

  • MCP servers publish from mcp/servers/<slug> (its own package.json, version and README).
  • ACP and A2A servers are repo-run today (Python, no packaging step).

Built on top of it

Creatures that use this corpus as their world live in the sibling repo mrfentmen/superagents (public, with its own claim-check in MISSING.md):

  • polymath — routes your question to the most fitting agents of this repo, spawns each as a real ACP child process, and merges the answers into one brief with per-row citations; a sibling that fails appears as a named row, never silence. Its registry is a data file and its ranking is deterministic word-scoring, not a model opinion.
  • sentry — one plain sentence ("watch air quality in Denver over 150") becomes a tracked watch: a permission-asked protocol write produces the conditions file this repo's watchd/ obeys unchanged, plus the activation lines. Checks it can author today: air thresholds, quake magnitudes within a radius, river gauges at flood stage.
  • fedora hat guy — the persona agent in his own repo mrfentmen/fedora-hat: says "never miss" and means it — one sentence installs the full crown of watches (air + quakes, gauge-named flood) in one permissioned write, and your other questions are forwarded to the siblings above with every row cited.
  • instink — the instinct agent in his own repo mrfentmen/instink: compiles a skill into a reflex — a matcher plus the answer it fires, with hit/miss counters and honest promotion/demotion. The skill doc stays one step away, never deleted.
  • contextink — the context agent in his own repo mrfentmen/contextink: you say "do this" and it acquires the context from the repo, git, and recent files so you don't have to explain it; asks only the minimal high-information-gain questions when acquisition fails.
  • rewind — the replay agent in his own repo mrfentmen/rewind: replays agent runs and mutates one variable to see what would have happened. Replay + mutate + diff for agent traces.
  • scopink — the scope agent in his own repo mrfentmen/scopink: checks if an action is within the scope of what was asked. Detects scope creep in agent plans.
  • curious — the curiosity agent in his own repo mrfentmen/curious: proactively seeks information it doesn't have. Scans for knowledge gaps, seeks answers, learns facts.
  • bored — the idle agent in his own repo mrfentmen/bored: uses idle time productively. Consolidates memories, explores areas, prepares for tasks.

Point the polymath at a checkout of this repo with AWESOME_SERVERS_HOME=$PWD/awesome-servers and it federates across the two repos live.

Published snapshot (published/)

published/ holds one directory per npm package, byte-for-byte what the registry serves: 1039 packages, every version matching npm latest.

  • published/INDEX.md is generated from the tree by python3 scripts/index-published.py.
  • scripts/sync-published-snapshot.py re-downloads every package from npm; run it only when every local fix has been published, because it overwrites dist/ from the tarballs.
  • One package carries a licence gate (MCP_LICENSE_KEY): @mrfentmen/vg-resource-mcp. Another 495 still ship tools that answer Not yet implemented; published/INDEX.md lists every one of them.
  • Every package links to this repo (mrfentmen/awesome-servers) as its source.

servers/ holds the older per-server source that predates the snapshot. Where the two disagree, published/ is what users actually install.

来源:README.md,提交 ee04f93

工具

4

list_genomes

Genomes hosted by UCSC, optionally filtered by name, organism or description.

输入参数limitquery

list_chromosomes

Chromosomes and scaffolds of one assembly, with sizes and the largest shown.

输入参数limitgenome必填

get_sequence

DNA sequence for a coordinate range, with length, GC content and N count.

输入参数end必填chrom必填start必填genome必填

search_genome

Search an assembly by gene or feature name and list the position matches with coordinates.

输入参数term必填limitgenome必填

版本历史

1
  1. v1.0.1最新Oct 29, 2026

评分

已满足适用检查项的 80%

该评分衡量此收录条目的完整程度,依据注册中心条目、端点与公开来源计算得出。它不是对服务器本身的评价,也不表示服务器安全或当前可用:可连通性是带日期的检查结果,评分也不包含安装量或用户评价。

  • 近 30 天内可连通25 分
  • 已声明认证方式10 分

    请在注册中心条目中声明凭据请求头,或保持端点能够响应探测,以便判定其认证方式。

  • 已列出工具必需15 分
  • 描述必需15 分
  • 图标10 分
  • 文档15 分
  • 许可证10 分

    请在仓库或注册中心条目中声明许可证。